Analysis Of Prospective Cohort Study Data - 916 Words

Statistical Analysis An objective of the analysis of prospective cohort study data is to compare disease occurrence in the group to the exposure factors. Disease occurrence is measured using cumulative incidence or incidence rates, and the relationship between exposure and disease occurrence is quantified by the cumulative incidence or incidence rate difference and ratio. Calculating an incidence rate involves determining the amount of person-time accrued by each study subject. Relative risks of each of the variables that are evaluated in the study are calculated. In addition, a Cox proportional hazard models is used to analyzed the relationship between environmental and genetic factors and type 1 diabetes mellitus. Persons-years were calculated for all the individuals from the beginning of the prospective cohort study until the end of the study or end due to loss to follow-up. The reasoning for utilizing the Cox proportional hazards models is because the study has continuous and multiple covariates. Ea ch of the factors need to be evaluate and compare in order to establish whether there is a relationship between environmental factors and the manifestation of type 1 diabetes mellitus. Multivariate analysis is necessary to implement due to the potential number of confounding variables in the study. Multivariate analysis involves the construction of a mathematical model that describes the association between exposure, disease, and confounders. This type of analysis isShow MoreRelatedCorrelation Between Acute Dysglycemia And Death Essay1043 Words   |  5 PagesThe study Serum Glucose Levels for Predicting Death in Patients Admitted to Hospital for Community Acquired Pneumonia: Prospective Cohort Study was published by the British Medical Journal (The BMJ) in the journal volume 344, number E3397, on May 29th of 2012. 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